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Calgary-based lab makes biotech strides

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Published: April 4, 2002

Protein-based products manufactured in a Calgary laboratory may help

relieve the discomfort of psoriasis and arthritis.

SemBioSys Genetics Inc., which grew out of University of Calgary

science labs, is manufacturing proteins produced in the seeds of

safflowers.

The company has been multiplying genetically altered safflowers in

southern Alberta for two years.

Plans are to step up production next year as more seed becomes

available.

SemBioSys chief executive officer Andrew Baum says this kind of crop

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production is the wave of the future, with its promise of premiums for

specialty crops.

“This is not a huge acreage opportunity, but it is a very high-value

opportunity for those people,” he said.

“A successful product for us is 2,000-3,000 acres per year.”

SemBioSys grew out of Maurice Moloney’s microbiology work with canola

proteins at the U of C, where he developed an anti-coagulant protein.

It became a separate company in 1994 and opened its lab in northeast

Calgary last summer.

The company employs 58 people in a 2,250 sq. metre facility.

For California-born Baum, the move to Calgary to head SemBioSys holds

promise. He started his career with the genetics company Calgen, which

was taken over by Monsanto in 1997.

While genetically modified organisms have received more than their

share of bad press, Baum is convinced his company’s product can receive

better acceptance than herbicide-tolerant crops.

“This type of production is completely different from anything people

have done before,” he said.

“Our objective is not to sell this to food manufacturers. Our objective

is to have a farmer produce a crop and we will buy it back and we will

process it so it will be an identity preserved production system,” he

said.

“That is a brand new form of agriculture.”

Baum said major mistakes were made during the early days of genetic

modification with products such as herbicide-tolerant oilseeds and

grain.

They were allowed into the general crop mix and some customers rejected

them.

He applauds the tough Canadian regulatory system and said people will

accept GM products if they are beneficial medications for chronic

conditions like arthritis, asthma, skin disorders and cholesterol

lowering drugs.

“We have to grow this under very rigorous, good agronomic practices

with rigorous operating procedures to ensure the entire crop never ends

up in the general mix,” he said.

“We don’t want this to become a deregulated industry. We want

government oversight and that the public is confident that we are doing

this right.”

Potential customers are large drug companies looking for a variety of

pharmaceuticals that can be produced at a lower cost.

However, these kinds of projects remain costly while they are in

development.

Part of Baum’s job has been to raise money. In the last 18 months he

has attracted $17 million in venture capital investments and plans to

garner an equal amount in the next year.

The Alberta venture capital company AVAC recently invested $2.4 million.

Dow Agro Services, University of Calgary and Moloney are major company

shareholders.

Calgary is an unusual location for a biotech company. Most are located

close to major investors and the major universities that specialize in

biotechnology.

The industry’s challenge is to find enough experienced people to

develop these companies.

“The industry is growing by about 12 percent a year so there is a

tremendous demand for the people who have actually done it,” Baum said.

About the author

Barbara Duckworth

Barbara Duckworth

Barbara Duckworth has covered many livestock shows and conferences across the continent since 1988. Duckworth had graduated from Lethbridge College’s journalism program in 1974, later earning a degree in communications from the University of Calgary. Duckworth won many awards from the Canadian Farm Writers Association, American Agricultural Editors Association, the North American Agricultural Journalists and the International Agriculture Journalists Association.

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