Pneumonia linked to hormone suppressing drug

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Published: November 21, 2002

A link found between estrus-suppressing drugs and pneumonia in cattle

could help feedlot operators cut losses in market-ready animals.

In a three-year study, Tim McAllister of the Agriculture Canada

Research Centre in Lethbridge found a link between heifer losses to

atypical interstitial pneumonia, or AIP, and the commonly fed

estrus-suppressing drug melengestrol acetate, or MGA.

Eliminating MGA from the diet reduced the risk of contracting AIP,

McAllister reported.

MGA is commonly given to heifers to keep them from mounting in pens,

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decrease damage to animals and maintain good weight gains, said Glenn

Coulter, the centre’s assistant director.

He said the disease affects less than one percent of cattle.

“It’s not a big problem, but you can lose five or seven animals per pen

at once,” Coulter said.

He expected there will be further study to better understand what is

happening and how it relates to weather factors.

The studies, which took place at the Lethbridge research centre,

southern Alberta feedlots, Alberta Agriculture, Ohio State University

and the University of Utah, also found that acetylsalicylic acid, or

ASA, could increase the short-term life expectancy of cattle with the

disease.

Researchers studied plasma, urine, lung tissue and rumen fluid from

slaughtered animals diagnosed with AIP and compared them with similar

samples from healthy animals given a host of experimental treatments.

They found heifers were more susceptible to AIP than steers.

McAllister believes MGA may increase the levels of an enzyme believed

to damage the lungs and lead to pneumonia in heifers at body weights of

around 1,000 pounds.

It causes symptoms such as frothing at the mouth, lowering of the head,

increases in respiration and grunting.

Gary Sargent, general manager of the Alberta Cattle Commission, called

it a troublesome disease, which struck the Picture Butte district two

years ago.

“People were experiencing losses and didn’t have an idea,” he said. “At

least now they will have some idea where to look.”

Sargent said producers concerned about the disease launched the

$210,000 project that studied 900,000 cattle. Funding came from the

Canada Alberta Beef Industry Development Fund, which was designed to

tackle problems facing Alberta beef producers and is administered by

the ACC.

About the author

Karen Morrison

Saskatoon newsroom

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